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Accident – Death – Obituary News : : 1. India lumpy skin cattle disease
2. Multi-institutional team virus study

A team of researchers from multiple institutions, including the Indian Institute of Science (IISc), has uncovered vital information about the evolution and origins of the virus strains responsible for the lumpy skin cattle disease outbreak in India. The outbreak, which began in May 2022, has claimed the lives of over 1,00,000 cows. The disease, caused by the Lumpy Skin Disease Virus (LSDV) transmitted by insects, has been a major concern for the country. Through advanced genomic analysis, the team identified two distinct LSDV variants circulating in India, shedding light on the severity of the disease and paving the way for improved diagnostics and interventions.

A multi-institutional team has recently shed light on the evolution and origins of the virus strains responsible for the devastating lumpy skin cattle disease outbreak in India. The Indian Institute of Science (IISc) has played a crucial role in uncovering critical insights into this alarming situation.

The outbreak, which began in May 2022, has resulted in the tragic loss of around 1,00,000 cows across the country. The lumpy skin disease, caused by the Lumpy Skin Disease Virus (LSDV), has wreaked havoc on cattle populations, leading to fever, skin nodules, and ultimately, fatal outcomes.

The LSDV, originally discovered in Zambia in 1931, was predominantly limited to the Sub-African region until 1989. Since then, it has spread to various parts of the world, including the Middle East, Russia, and now, South Asia. India has experienced two major outbreaks of this disease, with the most recent outbreak in 2022 infecting over two million cows.

To investigate the current outbreak, the team embarked on a comprehensive research endeavor, collecting samples from infected cattle in states like Gujarat, Maharashtra, Rajasthan, and Karnataka. Through advanced whole-genome sequencing techniques, they analyzed DNA extracted from 22 samples to unravel the genetic variations of the virus.

Their genomic analysis revealed two distinct LSDV variants circulating in India, each with its own set of genetic characteristics. One variant exhibited a low number of genetic variations, similar to strains identified in Ranchi and Hyderabad in previous years. On the other hand, the second variant displayed a high number of genetic variations, resembling strains from a past outbreak in Russia.

The presence of such highly varied LSDV strains in India was unprecedented, raising concerns about the severity of the disease. The team identified over 1,800 genetic variations, including deletions, insertions, and single-letter changes in DNA. These variations were found in genes critical for viral binding, immune evasion, and replication, potentially enhancing the virus’s pathogenicity.

The findings from this study are instrumental in guiding the development of diagnostics, vaccines, and interventions to combat emerging infectious diseases affecting livestock. By understanding the genetic landscape of the virus, researchers can target specific molecular hotspots and genetic variations to mitigate the impact of the disease.

This collaborative effort exemplifies the “One Health” approach, bringing together experts from various disciplines to address pressing issues in public health. The partnership between molecular biologists, computational experts, and veterinary doctors highlights the importance of interdisciplinary collaboration in tackling complex disease outbreaks.

Moving forward, the insights gained from this study will inform future strategies for managing lumpy skin disease and other emerging infectious threats to livestock and livelihoods. The research conducted by the team at IISc underscores the significance of proactive measures in safeguarding animal health and well-being. the latest developments in sustainable fashion trends for 2022.

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Overall, the sustainable fashion trends for 2022 are a reflection of the industry’s growing commitment to environmental and social responsibility. From upcycled materials to local production and circular fashion concepts, brands are finding new and innovative ways to reduce their impact on the planet and promote a more sustainable future. By embracing these trends and making conscious choices as consumers, we can all play a part in creating a more sustainable and ethical fashion industry.